Iranian Journal of Veterinary Surgery

Iranian Journal of Veterinary Surgery

Comparative Evaluation of Standing and Lateral Recumbency Restraint Positions for Rumenotomy Based on Transforming Growth Factor-β Responses in Kano-Brown Goats

Document Type : Original Article

Authors
Abubakar Mshelia Saidu 1
Samuel Fadason 2
Gabriel E. Ochube 2
Sani Adamu 3
1 Department of Veterinary Surgery and Radiology, University of Maiduguri, Maiduguri, Nigeria.
2 Department of Veterinary Surgery and Radiology Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
3 Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
10.30500/ivsa.2020.213380.1206
Abstract
Objective- Comparative evaluation of standing and lateral recumbent restraint positions for rumenotomy based on transforming growth factor-β (TGF-β) concentrations of Kano-Brown goats (KBGs).
Design- Experimental study
Animals- Eighteen KBGs of both sexes diagnosed of rumen foreign body impaction (RFBI), were allocated to groups A, B and D. Six other KBGs free of RFBI were assigned to group C as control.
Procedures- Groups A and B were restrained in lateral recumbency position while group D in a fabricated mobile small ruminant surgical chute (MSRSC) in a standing fashion. Serum samples stored at -20 ℃ until ELISA, were obtained pre-rumenotomy (Pre) and post-rumenotomy, at 0, 5, 24, 48 and 72 hours, and subsequently at weeks 1, 2, and 3. Group C had no surgery while A, B and D had rumen skin clamp fixation, stay suture rumenotomy and mobile small ruminant surgical chute rumenotomy, respectively.
Results- The post-rumenotomy mean concentrations of TGF-β for groups A, B and D at 0 hour (81.97 ± 24.12, 71.26 ± 10.28 and 58.51 ± 6.44 ng/L, respectively) were higher than the mean pre-rumenotomy values (38.34 ± 3.66, 41.31 ± 4.90 and 44.91 ±4.10 ng/L, respectively) but were not significantly different (P > 0.05). As the mean TGF-β concentration in the males of the different experimental groups did not differ significantly (P > 0.05), the females of group B had significantly higher (P < 0.05) mean concentrations than those of group D and C females at 48 hours post-rumenotomy.
Conclusions and Clinical Relevance- Lateral recumbency restraint position rumenotomy was associated with more severe post-surgical stress than standing restraint based on role switching of the TGF-β in this study. This suggests comparative advantage of standing recumbency restraint rumenotomy over the conventional lateral recumbency restraints position in goats.
Keywords
Surgical stress
Caprine
Rumen
Chute
Cytokines
ELISA

Subjects

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  • Receive Date 27 December 2019
  • Revise Date 01 February 2020
  • Accept Date 10 February 2020
  • First Publish Date 01 April 2020