@article { author = {Mshelia Saidu, Abubakar and Fadason, Samuel and Ochube, Gabriel and Adamu, Sani}, title = {Comparative Evaluation of Standing and Lateral Recumbency Restraint Positions for Rumenotomy Based on Transforming Growth Factor-β Responses in Kano-Brown Goats}, journal = {Iranian Journal of Veterinary Surgery}, volume = {15}, number = {1}, pages = {24-31}, year = {2020}, publisher = {Iranian Veterinary Surgery Association (IVSA)}, issn = {2008-3033}, eissn = {2676-6299}, doi = {10.30500/ivsa.2020.213380.1206}, abstract = {Objective- Comparative evaluation of standing and lateral recumbent restraint positions for rumenotomy based on transforming growth factor-β (TGF-β) concentrations of Kano-Brown goats (KBGs).Design- Experimental studyAnimals- Eighteen KBGs of both sexes diagnosed of rumen foreign body impaction (RFBI), were allocated to groups A, B and D. Six other KBGs free of RFBI were assigned to group C as control.Procedures- Groups A and B were restrained in lateral recumbency position while group D in a fabricated mobile small ruminant surgical chute (MSRSC) in a standing fashion. Serum samples stored at -20 ℃ until ELISA, were obtained pre-rumenotomy (Pre) and post-rumenotomy, at 0, 5, 24, 48 and 72 hours, and subsequently at weeks 1, 2, and 3. Group C had no surgery while A, B and D had rumen skin clamp fixation, stay suture rumenotomy and mobile small ruminant surgical chute rumenotomy, respectively. Results- The post-rumenotomy mean concentrations of TGF-β for groups A, B and D at 0 hour (81.97 ± 24.12, 71.26 ± 10.28 and 58.51 ± 6.44 ng/L, respectively) were higher than the mean pre-rumenotomy values (38.34 ± 3.66, 41.31 ± 4.90 and 44.91 ±4.10 ng/L, respectively) but were not significantly different (P > 0.05). As the mean TGF-β concentration in the males of the different experimental groups did not differ significantly (P > 0.05), the females of group B had significantly higher (P < 0.05) mean concentrations than those of group D and C females at 48 hours post-rumenotomy. Conclusions and Clinical Relevance- Lateral recumbency restraint position rumenotomy was associated with more severe post-surgical stress than standing restraint based on role switching of the TGF-β in this study. This suggests comparative advantage of standing recumbency restraint rumenotomy over the conventional lateral recumbency restraints position in goats.}, keywords = {Surgical stress,Caprine,Rumen,Chute,Cytokines,ELISA}, url = {https://www.ivsajournals.com/article_102830.html}, eprint = {https://www.ivsajournals.com/article_102830_81ff8ade77c24ac9e8f00cde9314e250.pdf} }