Document Type : Original Article
1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Shiraz University, Shiraz, Iran.
2 Department of Surgery, School of Medicine, Laparoscopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
The purpose of this study is to evaluate the effects of gastric bypass surgery and sleeve gastrectomy on vitamin B12 values in dogs. Gastric dilation and volvulus (GDV) is an acute disease with a high mortality rate in dogs. Either gastric bypass surgery or sleeve gastrectomy can be utilized as surgical treatments for GDV. These techniques can provide increased success and fewer complications, however, one undesirable outcome can be vitamin B12 insufficiency. Three groups of dogs received gastric surgeries, one group underwent gastric rotation and derotation with no tissue gastric incisions, the two other groups had gastric bypass surgery and sleeve gastrectomy. Vitamin B12 level was evaluated two weeks prior to surgery, at the time of surgery, two, four, and six weeks after surgery. The results demonstrated no inter-group differences two weeks prior to surgery until four weeks after surgery. However, six weeks post-operation, significant differences between the sleeve gastrectomy group, and the other two groups were shown in vitamin B12 levels. Gastric bypass surgery and sleeve gastrectomy can both be utilized as new surgical managements of GDV. However, as we have demonstrated in this article, an important expected side effect is vitamin B12 insufficiency, in dogs that receive sleeve gastrectomy for GDV treatment. This necessary element must be substituted artificially for all dogs which had received these surgical managements.
- Wang Y, Beydoun MA, Liang L, Caballero B, Kumanyka SK. Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic. Obesity. 2008;16:2323-2330.
- Haddock CK, Poston WS, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials. International Journal of Obesity and Related Metabolic Disorders. 2002;26:262-273.
- Crookes PF. Surgical treatment of morbid obesity. Annual Review of Medicine. 2006;57:243-264.
- Garb J, Welch G, Zagarins S, Kuhn J, Romanelli J. Bariatric surgery for the treatment of morbid obesity: a meta-analysis of weight loss outcomes for laparoscopic adjustable gastric banding and laparoscopic gastric bypass. Obesity Surgery. 2009;19:1447-1455.
- Heal DJ, Gosden J, Smith SL. A review of late-stage CNS drug candidates for the treatment of obesity. International Journal of Obesity. 2013;37:107-117.
- Sjostrom, L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, Dahlgren S, Larsson B, Narbo K, Sjostrom CD. Lifestyle, diabetes and cardiovascular risk factors 10 years after bariatric surgery. New England Journal of Medicine. 2004;351:2683-2639.
- Simpson KW, Morton DB, Batt RM. Effects of exocrine pancreatic insufficiency on cobalamin absorption in dogs. American Journal of Veterinary Research. 1989;50:1233-1236.
- Ballantyne GH. Peptide YY (1-36) and peptide YY (3-36): Part l. Distribution, release and action. Obesity Surgery. 2006;16:651-658.
- Valderas JP, Irribarra V, Boza C, Cruz R, Liberona Y, Acosta AM, Yolito M, Maiz A. Medical and surgical treatment for obesity have opposite effects on peptide YY and appetite: a prospective study controlled for weight loss. Journal of Clinical Endocrinology and Metabolism. 2010;95:1069-1075.
- Mackenzie G, Barnhart M, Kennedy S, DeHoff W, Schertel E. A retrospective study of factors influencing survival following surgery for gastric dilatation-volvulus syndrome in 306 dogs. Journal of the American Animal Hospital Association. 2010;46(2): 97-102.
- Pipan M. Brown DC, Battaglia CL, Otto CM. An internet-based survey of risk factors for surgical gastric dilatation-volvulus in dogs. Journal of the American Veterinary Medical Association. 2012;240(12):1456-1462.
- Schertel ER, Allen DA, Muir WW, Brouman JD, DeHoff WD. Evaluation of a hypertonic saline-dextran solution for treatment of dogs with shock induced by gastric dilatation-volvulus. Journal of the American Veterinary Medical Association. 1997;210:226-230.
- Williams JM, Niels JD. BSAVA manual of canine and feline abdominal surgery. 2nd ed. Gloucester: British Small Animal Veterinary Association; 2016:89-103.
- Psatha E, Alibhai HIK, Jimenez-Lozano A, Armitage-Chan E, Brodbelt DC. Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anesthesia in dogs that are a poor anesthetic risk. Veterinary Anaesthesia and Analgesia. 2011;38(1):24-36.
- Mechanick JI, Youdim A, Jones DB, Garvey WT, Hurley DL, McMahon MM, Heinberg LJ, Kushner R, Adams TD, Shikora S. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient. Obesity. 2013;(1):21-27.