Iranian Journal of Veterinary Surgery

Iranian Journal of Veterinary Surgery

Comparison of Synovial Fluid Composition in Distended and Normal Digital Flexor Tendon Sheath of Horses (A Pilot Study)

Document Type : Original Article

Authors
Zahra Noori
Samaneh Ghasemi
Ali Mirshahi
Mehdad Mohri
Ahmadreza Mohamadnia
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
10.30500/ivsa.2021.296292.1273
Abstract
Diagnosis of tenosynovitis is usually confirmed on the basis of synovial fluid analysis (such as cytological and biochemical examinations). This study was designed to examine biochemical (serum amyloid A (SAA), haptoglobin (Hp) and D-dimer) and cytological (total nucleated cell count (TNCC), neutrophil, lymphocyte, and monocyte count) characteristics of serum and synovial fluid of the equine digital flexor tendon sheath (DFTS). Synovial fluid samples were aseptically collected in EDTA from 43 limbs in 20 horses with (study group) and 8 limbs in 8 horses without (control group) distention of DFTS and serum samples were collected from each horse. Lymphocyte, monocyte, neutrophil, and TNCC in the synovial fluid were statistically higher in the distended sheath that shows an inflammatory nature of the distention, however, concentrations of D-dimer was lower in serum (0.1, 0.10-3.80) and (0.2, 0.10-0.20) than synovial fluid (19.2, 17.78-20.00) and (20, 19.90-20.00)) in both groups. The serum SAA concentrations of the control group (1.7, 0.10-2.16) were significantly higher than the study group (1, 0.86-1.05) and the concentration of SAA in serum was higher than synovial fluid (0.89, 0.86-0.98) in the control group. Results of this current study show that a cytological evaluation of the synovial fluid is more valuable than biochemical findings in the diagnosis of the inflammatory nature of this condition.
Keywords
Digital flexor tendon sheath
Haptoglobin
Total nucleated cell count
Serum amyloid A
D-dimer

Subjects

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Iranian Journal of Veterinary Surgery
Volume 16, Issue 2 - Serial Number 35
October 2021
Pages 107-114

  • Receive Date 22 July 2021
  • Revise Date 20 August 2021
  • Accept Date 23 August 2021
  • First Publish Date 23 August 2021