%0 Journal Article %T Comparison of Lidocaine, Xylazine, and a Combination of Lidocaine and Xylazine for Caudal Epidural Analgesia in Dromedary Camels %J Iranian Journal of Veterinary Surgery %I Iranian Veterinary Surgery Association (IVSA) %Z 2008-3033 %A Molaei, Mohammad Mahdi %A Azari, Omid %A Sakhaee, Ehsanollah %A Naderi, Zahedeh %A Mehdizadeh, Sara %D 2010 %\ 08/01/2010 %V 05 %N 1-2 %P 51-62 %! Comparison of Lidocaine, Xylazine, and a Combination of Lidocaine and Xylazine for Caudal Epidural Analgesia in Dromedary Camels %K Epidural %K Lidocaine %K Xylazine %K Dromedary Camels %R %X Objective- This study was performed to investigate the analgesic effects of lidocaine, xylazine and lidocaine/xylazine combination in epidural anesthesia in dromedary camels.Design- Experimental StudyAnimals- Fifteen healthy immature dromedary camelsMethods- The camels were randomly designed in 3 equal groups. In group L: lidocaine 2% (0.22 mg/kg), in group X: xylazine 2% (0.17 mg/kg), and in group LX: a combination of lidocaine 2% (0.22 mg/kg) and xylazine 2% (0.17 mg/kg) were injected into the first intercoccygeal epidural space. Analgesia, sedation, ataxia, and effect on cardiopulmonary, rectal temperature were recorded at different intervals before (baseline) and after the drug administration.Results- Epidural lidocaine, xylazine and their combination produced analgesia in the tail, anus and perineum. Onset time of perineal analgesia in groups L and LX was significantly shorter than group X. Duration of complete perineal analgesia in group X and LX was significantly longer than group L. Mild to moderate sedation was observed in groups X and LX, whilst the camels in group L were alert and nervous during the study. Ataxia was observed in all test subjects and was more severe in group L and LX. Significant depression in heart rate, respiratory rate, and rectal temperature values were observed in groups X and LX in some measurement points of the study.Conclusion and Clinical Relevance- According to the results of present study, it could be concluded that a combination of lidocaine and xylazine administered epidurally to dromedaries produces an effective, safe, with more rapid onset of longer perineal analgesia, when compared with either agent alone. %U https://www.ivsajournals.com/article_3143_a94fdae2ff9a52d0bc4416ce2d723e61.pdf