ORIGINAL_ARTICLE
Evaluation of Etomidate as an Intravenous Anesthetic Drug in Dogs: Using Midazolam and Methocarbamol in Premedication
Objective- The aim of this study was to evaluate etomidate as an injectable anesthetic in dogs and to use midazolam and methocarbamol as premedication.Design- Experimental Study.Animals- Fourteen native young female dogsProcedure- Dogs were randomly allocated to two groups to receive midazolam (0.5 mg/kg; MiE group) or methocarbamol (20 mg/kg; MeE group) 5 minute before etomidate (2 mg/kg) intravenously. In addition to recording anesthesia time table, physiological and hematobiochemical parameters were also measured at different time points in two groups.Results- It was found that there was no significant difference between two groups at both induction and recovery time. Heart rate, respiratory rate, and rectal temperature changes in the MiE group were noticeably fluctuating, unlike the MeE group. There was a significant difference in the values of hematocrit, total protein, glucose, and cortisol between the two groups at some time points. Significant increase in ALT and AST activities was observed in MeE group compared to MiE group at some time points.Conclusion and Clinical Relevance- Intramuscular administration of methocarbamol or midazolam prior to etomidate not only has minimal cardiopulmonary effects and hematobiochemical changes in dogs but provide similar anesthesia and recovery time.
https://www.ivsajournals.com/article_111549_43628b9c51d861e6b96e446f3f83d852.pdf
1999-11-30
96
105
10.30500/ivsa.2020.225832.1213
Etomidate
Midazolam
Methocarbamol
Dog
Moosa
Javdani
javdani59@gmail.com
1
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
LEAD_AUTHOR
Ali
Hashemi
sayedalihashemi1370@gmail.com
2
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
AUTHOR
Amin
Bigham-Sadegh
dr.bigham@gmail.com
3
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
AUTHOR
Zahra
Nikousefat
yaldanikousefat@gmail.com
4
Department of Clinical sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
AUTHOR
Hohl CM, Kelly-Smith CH, Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Annals of Emergency Medicine, 2010; 56(2): 105-113.
1
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Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA. Lumb and Jones Veterinary anesthesia and analgesia. 5th ed. John Wiley & Sons, Inc., 2015: 248-285.
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Mair AR, Pawson P, Courcier E, Flaherty D. A comparison of the effects of two different doses of ketamine used for co-induction of anaesthesia with a target-controlled infusion of propofol in dogs. Veterinary Anaesthesia and Analgesia, 2009; 36(6): 532-538.
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Hopkins A, Giuffrida M, Larenza MP. Midazolam, as a co‐induction agent, has propofol sparing effects but also decreases systolic blood pressure in healthy dogs. Veterinary Anaesthesia and Analgesia, 2014; 41(1): 64-72.
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Riccó CH, Henao-Guerrero N. Cardiovascular effects of orotracheal intubation following anesthetic induction with propofol, ketamine-propofol, or ketamine-diazepam in premedicated dogs. Journal of the American Veterinary Medical Association, 2014; 244(8): 934-939.
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Jones DJ, Stehling LC, Zauder HL. Cardiovascular responses to diazepam and midazolam maleate in the dog. Anesthesiology, 1979; 51(5): 430-434.
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Ko JC, Thurmon JC, Benson GJ, Tranquilli WJ, Olson WA, Vaha-Vahe AT. Hemodynamic and anesthetic effects of etomidate infusion in medetomidine-premedicated dogs. American Journal of Veterinary Research, 1994; 55(6): 842-846.
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42
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43
ORIGINAL_ARTICLE
Effect of Short Term Oral Administration of Silymarin on Healing of Colonic Anastomosis in Rats
Objective- Leakage after colon anastomosis is the most common complication with the highest mortality rate. Silymarin possesses potent anti-inflammatory, antioxidant, reparative and antibacterial activities and therefore has been used to accelerate different experimental wound healing models. This study was aimed to investigate effects of orally administered silymarin following colonic resection and anastomosis in terms of histopathological and mechanical parameters. Design- An experimental study.Animals- Twenty four male mature Wistar ratsProcedures- The rats were divided randomly into two groups. After aseptic preparation, descending colon was exteriorized thorough laparotomy. Then, colon resection and end to end anastomosis was performed in all rats. The control rats were gavaged with 1 ml normal saline post operatively as placebo while the rats in the treatment group received 50 mg/kg silymarin suspended in 1 ml normal saline for five consecutive days. At the 7th day, all rat were euthanized. Results- Necropsy finding showed that leakage, adhesion formation and peritonitis scores in treatment group were significantly decreased. On histopathology, decreased inflammatory cell infiltration was observed in the treatment group. While, the scores of angiogenesis, cell proliferation, and collagen deposition were significantly increased in the treatment group. No significant difference was observed in bursting pressure when control samples were compared to the silymarin treated ones. Furthermore, mechanical properties (including: maximum load, yield load, and absorbed energy) in treatment group were significantly increased compared to control group. Conclusion and Clinical Relevance- The results of the present study showed that oral administration of silymarin following colonic anastomosis in rats improves the structural indices of wound healing and its mechanical characteristics with lower rates of anastomotic complications.
https://www.ivsajournals.com/article_115077_39975f2c86e24a0d5cb567e293d4f558.pdf
2020-12-01
106
114
10.30500/ivsa.2020.241541.1220
Adhesion
Burst pressure
collagen
Silymarin
tensile strength
Mozhgan
Malekolkalami
mozhganmalekolkalami@yahoo.com
1
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
AUTHOR
Mehdi
Behfar
m.behfar@urmia.ac.ir
2
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
LEAD_AUTHOR
Ali-Asghar
Tehrani
manijehid@yahoo.com
3
Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
AUTHOR
Clifford RE, Fowler H, Govindarajah N, Vimalachandran D, Sutton PA. Early anastomotic complications in colorectal surgery: a systematic review of techniques for endoscopic salvage. Surgical Endoscopy, 2019; 33(4):1049-1065.
1
Radlinsky MG, Fossum TW. Surgery of the digestive system. In: Fossum TW. Small animal surgery. Philadelphia: Elsevier; 2019: 331-511.
2
Ho YH, Ashour MA. Techniques for colorectal anastomosis. World Journal of Gastroenterology, 2010; 16(13): 1610-1621.
3
Ikada Y. Challenges in tissue engineering. Journal of the Royal Society Interface, 2006; 3(10): 589-601.
4
Drmic D, Kolenc D, Ilic S, Bauk L, Sever M, Zenko Sever A, Luetic K, Suran J, Seiwerth S, Sikiric P. Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME. World Journal of Gastroenterology, 2017; 23(29): 5304-5312.
5
Lin D, Chen K, Xie M, Ye L, Chan EW, Chen S. Effect of ceftiofur and enrofloxacin on E. coli sub-population in pig gastrointestinal tract. Journal of Global Antimicrobial Resistance, 2017; 10: 126-130.
6
Ashkani-Esfahani S, Emami Y, Esmaeilzadeh E, Bagheri F, Namazi MR, Keshtkar M, Khoshneviszadehd M, Noorafshane A. Silymarin enhanced fibroblast proliferation and tissue regeneration in full thickness skin wounds in rat models; a stereological study. Journal of the Saudi Society of Dermatology & Dermatologic Surgery, 2013; 17(1): 7-12.
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Katiyar SK. Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects (Review). International Journal of Oncology, 2005; 26(1): 169-176.
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Esmaily H, Hosseini-Tabatabaei A, Rahimian R. Khorasani R, Baeeri M, Barazesh Morgani AR, Yasa N, Khademi Y, Abdollahi M. On the benefits of silymarin in murine colitis by improving balance of destructive cytokines and reduction of toxic stress in the bowel cells. Central European Journal of Biology, 2009; 4: 204.
9
Cruz T, Gálvez J, Crespo E, Ocete MA, Zarzuelo A. Effects of silymarin on the acute stage of the trinitrobenzenesulphonic acid model of rat colitis. Planta Medica, 2001; 67(1): 94-96.
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Rastegarpanah M, Malekzadeh R, Vahedi H, Mohammadi M, Elahi E, Chaharmahali M, Safarnavadeh T, Abdollahi M. A randomized, double blinded, placebo-controlled clinical trial of silymarin in ulcerative colitis. Chinese Journal of Integrative Medicine, 2015; 21(12) :902-906.
11
Kisli E, Ozdemir H, Kösem M, Sürer H, Ciftçi A, Kanter M. Effect of Ginkgo biloba extract (EGb 761) on the healing of left colonic anastomoses in rat. World Journal of Surgery, 2007; 31(8): 1652-1657.
12
Despoudi K, Mantzoros I, Ioannidis O, Cheva A, Antoniou N, Konstantaras D, Symeonidis S, Pramateftakis MG, Kotidis E, Angelopoulos S, Tsalis K. Effects of albumin/glutaraldehyde glue on healing of colonic anastomosis in rats. Gastroenterology, 2017; 23(31): 5680-5691.
13
Wu Z, Daams F, Boersema GS, Vakalopoulos KA, Lam KH, van der Horst PH, Kleinrensink GJ, Jeekel J, Lange JF. Colorectal anastomotic leakage caused by insufficient suturing after partial colectomy: a new experimental model. Surgical Infections (Larchmt), 2014; 15: 733-738.
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Lorenzi T, Trombettoni MMC, Ghiselli R, Paolinelli F, Gesuita R, Cirioni O, Provinciali M, Kamysz W, Kamysz E, Piangatelli C, Castellucci M, Guerrieri M, Morroni M. Effect of omiganan on colonic anastomosis healing in a rat model of peritonitis. American Journal of Translational Research, 2017; 9(7): 3374-3386.
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Tallón-Aguilar L, Lopez-Bernal Fde A, Muntane-Relat J, García-Martínez JA, Castillo-Sanchez E, Padillo-Ruiz J. The use of TachoSil as sealant in an experimental model of colonic perforation. Surgical Innovation, 2015; 22(1): 54-60.
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Thomas MS, Margolin DA. Management of colorectal anastomotic leak. Clinics in Colon and Rectal Surgery, 2016; 29(2): 138-144.
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Takhshid M, Rosta A, Tavasouli A, Khabaz Z. Protective effects of silymarin on acetic acid –induced colitis in rats. Journal of Mazandaran University of Medical Sciences, 2011; 21(84): 53-61.
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Toutouzas K, Kleidi ES, Drimousis PG, Balla M, Papanikolaou MN, Larentzakis A, Theodorou D, Katsaragakis S. Anastomotic leak management after a low anterior resection leading to recurrent abdominal compartment syndrome: a case report and review of the literature. Journal of Medical Case Reports, 2009; 3: 125.
19
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Karimi M, Parsaei P, Shafiei-Alavijeh S, Rafieian-Kopaei M, Asadi SY. Effect of silymarin alcoholic extract on surgery-induced intraperitoneal adhesion in rats. Surgical Practice, 2016; 20(1): 27-33.
21
Tabandeh MR, Oryan A, Mohhammad-Alipour A, nd Tabatabaei-Naieni A. Silibinin regulates matrix metalloproteinase 3 (stromelysine1) gene expression, hexoseamines and collagen production during rat skin wound healing. Phytotherapy Research, 2013; 27: 1149-1153.
22
Stumpf M, Cao W, Klinge U, Klosterhalfen B, Kasperk R, Schumpelick V. Collagen distribution and expression of matrix metalloproteinases 1 and 13 in patients with anastomotic leakage after large-bowel surgery. Langenbeck's Archives of Surgery, 2002; 386(7): 502-506.
23
Munireddy S, Kavalukas SL, Barbul A. Intra-abdominal healing: gastrointestinal tract and adhesions. Surgical Clinics of North America, 2010; 90(6): 1227-1236.
24
Mastboom WJ, Hendriks T, van Elteren P, de Boer HH. The influence of NSAIDs on experimental intestinal anastomoses. Diseases of the Colon & Rectum, 1991; 34(3): 236-243.
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Davies NM. Toxicity of nonsteroidal anti-inflammatory drugs in the large intestine. Diseases of the Colon & Rectum, 1995; 38(12): 1311-1321.
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Hendriks T, Mastboom WJ. Healing of experimental intestinal anastomoses. Parameters for repair. Diseases of the Colon & Rectum, 1990; 33: 891-901.
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Månsson P, Zhang XW, Jeppsson B, Thorlacius H. Anastomotic healing in the rat colon: comparison between a radiological method, breaking strength and bursting pressure. International Journal of Colorectal Disease, 2002; 17(6): 420-425.
29
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31
Haugh MG, Jaasma MJ, O'Brien FJ. The effect of dehydrothermal treatment on the mechanical and structural properties of collagen-GAG scaffolds. Journal of Biomedical Materials Research, 2009; 89(2): 363-369.
32
ORIGINAL_ARTICLE
Intramedullary Pining versus Tape Splinting for Fixation of Tibiotarsal Fractures in Small Cage Birds: An Experimental Study
Objective- Tibiotarsal bone is the most commonly fractured long bone in small companion birds. The treatment options are basically limited to tape splinting the leg due to anatomical limitations. The goal of this study was to investigate intramedullary pinning (IM pin) as an alternative treatment option.Design- Experimental studyAnimals- Thirty mature budgerigars with an average weight of 30 g. Procedures- The birds underwent mid shaft tibiotarsus osteotomy and the fractures were managed by tape splinting or IM pining in each group. The IM pins and splints were removed at 21st day after surgery. Radiology was performed at 0, 7, 14, 21 and 28 days after surgery. Histopathological and biomechanical evaluations were performed on specimens by day 28. Stability on palpation, lameness scores and mortality rate were recorded.Results- Radiography showed perfect bone healing in the IM pin group versus the presence of malunion and deformity in the splint group. Histopathology demonstrated a more advanced bone healing in the IM pin group, characterized by the dominance of new bone trabeculae and new cortex formation with very little fibrous tissue. Biomechanical tests revealed significantly higher yield load, ultimate load, stiffness, and absorbed energy in the IM pin group (p <0.05). Lameness scores were significantly better in the tape splint group (p <0.05) and the mortality rate was 0 in the splint group versus 33% in the IM pin group.Conclusion and Clinical relevance- Although IM pinning showed a more advanced level of bone healing radiographically, histopathologically, and biomechanically, the higher mortality rate and higher lameness scores make it a less desirable choice for pet birds. IM pinning technique did not prove to be as safe as the tape splintage technique. Tape splinting remains the gold standard in managing the fractures of the tibiotarsal bone in budgerigars as it offers low risk and high acceptability.
https://www.ivsajournals.com/article_117712_43234a8b315d371f56c34ca8eed8497a.pdf
2020-04-01
115
122
10.30500/ivsa.2020.238408.1219
Budgerigar
Fracture Healing
IM pin
Splint
tibiotarsus
Hayede
Jalilpour
1
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz university, Shiraz, Iran.
AUTHOR
Abdolhamid
Meimandi-Parizi
maimanp1@yahoo.com
2
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz university, Shiraz, Iran.
LEAD_AUTHOR
Azizollah
Khodakaram-Tafti
tafti_a@shirazu.ac.ir
3
Department of Pathobiology, School of Veterinary Medicine, Shiraz university, Shiraz, Iran.
AUTHOR
Mohamad Saeed
Ahrari-Khafi
ahrari@shirazu.ac.ir
4
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz university, Shiraz, Iran.
AUTHOR
Seyedreza
Hashemi
5
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz university, Shiraz, Iran.
AUTHOR
Coles B. Surgery. Essentials of avian medicine and surgery. 3rd ed. Oxford, UK: Blackwell Publishing Ltd, 2007; 144-145.
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Wright L, Mans C, Olsen G, Doss G, Amene EW, Britsch G, Christman J, Heatley J. Retrospective evaluation of tibiotarsal fractures treated with tape splints in birds: 86 cases (2006–2015). Journal of Avian Medicine and Surgery, 2018; 32(3): 205-209.
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14
De Conti JB, Schossler JE, Alievi MM, Bonfada AT, Novosad D, Silva D, Pachaly JR Use of type II external skeletal fixator for tibiotarsus osteosynthesis in white Plymouth Rock chickens: an experimental model for using in wild birds. Pesquisa Veterinaria Brasileira, 2007; 27(5): 199-204.
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Bueno I, Redig PT, Rendahl AK. External skeletal fixator intramedullary pin tie-in for the repair of tibiotarsal fractures in raptors: 37 cases (1995–2011). Journal of the American Veterinary Medical Association, 2015; 247(10): 1154-1160.
20
Bennert BM, Kircher PR, Gutbrod A, Riechert J, Hatt JM. Evaluation of two miniplate systems and figure-of-eight bandages for stabilization of experimentally induced ulnar and radial fractures in pigeons (Columba livia). Journal of Avian Medicine and Surgery, 2016; 30(2): 111-121.
21
Gouvea AS, Alievi MM, Noriega V, Dal-Bó ÍD, Pinto TM, Menezes CL, Silva RB, Silva LM, Velasque AG, Pinto LA, Coelho AJ. Titanium microplates for treatment of tibiotarsus fractures in pigeons. Ciência Rural, 2011; 41(3): 476-483.
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31
ORIGINAL_ARTICLE
Comparison of the Effect of Lidocaine in Combination to Meloxicam and/or Metamizole Sodium Epidurally on Analgesic Parameters, and Health Status of Holstein Cattle
Objective- This practice performed to compare the quality of analgesia, hematological parameters, and prevalence of cardiac dysrhythmias following epidural administration of lidocaine, lidocaine-meloxicam, and lidocaine-Metamizole sodium in cows.Animals- Fifteen adult Holstein cows aged between 3-5 years were assigned into three equal groups. Design- Each cow received the lidocaine (0.22 mg/kg), lidocaine-meloxicam (0.11 mg/kg – 0.25 mg/kg) or lidocaine-Metamizole sodium (0.11 mg/kg -4 mg/kg) randomly via epidural injection into first intercoccygeal space. Procedure- Analgesia onset and duration were recorded. Heart rate, respiratory rate, rectal temperature, and ruminal motility were also recorded at 0, 5, 15, 30, 45, 60, 90 and 120 minutes, Electrocardiograms at 0, 60 and 120 minutes and blood samples were collected through the caudal vein at 0, 30, 60, 90 and 120 minutes. Detection of arrhythmias was done by checking 60 seconds of each electrocardiogram.Results- analgesia onset in lidocaine-metamizole treatment was significantly longer than that of the other groups (p 0.05). Also, the duration of analgesia was significantly longer in lidocaine treatment compared to other experimental groups (p <0.05). There were no significant differences among heart rate, respiratory rate, rectal temperature, and ruminal motility between experimental groups (p >0.05). Hematological parameters changes were not significantly different and all of the detected cardiac arrhythmias were physiologic among treatments (p > 0.05).Conclusions and Clinical Relevance- Aforementioned dosages could be used in cows without any clinical, cardiac, and hematological side effects. Lidocaine analgesia was reliable; however, the authors were not sure about adequate analgesia resulted after injection the half-dose of meloxicam and Metamizole in combination with lidocaine therefore, further studies should be done.
https://www.ivsajournals.com/article_114588_e698b6bee4cd129d76d90fe03aa7f6d4.pdf
2020-12-01
123
132
10.30500/ivsa.2020.244439.1222
Epidural Analgesia
Electrocardiography
Lidocaine
Meloxicam/Metamizole
Cow
Khosro
Safari-Nikoo
safarikhosro@yahoo.com
1
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Abbas
Raisi
raisi.a@lu.ac.ir
2
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
LEAD_AUTHOR
Amir
Zakian
amir.zakian7@gmail.com
3
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Ahmad Reza
Mohamadnia
mohamadnia@um.ac.ir
4
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Iran.
AUTHOR
Ragab GA, Fathy MZ. Evaluation of the epidural analgesic effect of nalbuphine, lidocaine and nalbuphine-lidocaine combination in bucks. Beni-Suef University Journal of Basic and Applied Sciences,2018; 7(1): 27-30.
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45
ORIGINAL_ARTICLE
Fabrication and Usage of a Nanocomposite Scaffold in Segmental Bone Healing: An Animal Model Study
Objective- The loss of bone fragments, often due to trauma, infection, mass loss, or even complete bone regeneration after complicated fractures, is one of the constant challenges in medicine and veterinary medicine. The aim of this study was to fabricate and use a nanocomposite scaffold in segmental bone healing in rabbits.Design- Experimental StudyAnimals- Forty adult male New Zealand male rabbitsProcedures- The animals were randomly divided into four groups of 10 animals each. On femur of each rabbit a bilateral 6 mm diameter defect was created. In the first group (control), no substance was used, in the second group, hydroxyapatite, in the third group, nanocomposite tri-calcium phosphate (TCP) and in fourth group, autograft was used to fill the defect. Bone specimens were harvested for histopathological evaluations on days 15 and 60 for evaluation of four indices of union, spongiosa, cortex and bone marrow. Results- The results of using nanocomposite tricalcium phosphate in comparison with other groups were significantly different in all cases. Conclusion and Clinical Relevance- It could be admitted that nanocomposite tri-calcium phosphate scaffold had a positive effect on the healing process and showed satisfactory bone strength, therefore, it could be widely used in orthopedic surgery as well as tissue engineering.
https://www.ivsajournals.com/article_119965_f9dd55ffcfeea3fbe023423ca61f7f1e.pdf
2020-12-01
133
140
10.30500/ivsa.2020.254705.1230
Nanocomposite
tricalcium phosphate/collagen
histopathology
Bone healing
animal model
Mahmoud
Mohseni
mohseni.mahmoud@gmail.com
1
Department of Veterinary Surgery, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Alireza
Jahandideh
dr.jahandideh@gmail.com
2
Department of Veterinary Surgery, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
LEAD_AUTHOR
Gholamreza
Abedi
abedi.gh.ch@gmail.com
3
Department of Veterinary Surgery, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Abolfazl
Akbarzadeh
akbarzadehab@tbzmed.ac.ir
4
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Saeed
Hesaraki
saeed.hesaraki@gmail.com
5
Department of Pathobiology, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Gentile P, Chiono V, Carmagnola I, Hatton PV. An overview of poly(lactic-co-glycolic) acid (PLGA)-based biomaterials for bone tissue engineering. International journal of Molecular Science, 2014; 15(3): 3640-3659.
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3
Kim KJ, Choi MS, Shim JH, Rhie JW. Bone morphogenetic protein 2-conjugated silica particles enhanced early osteogenic differentiation of adipose stem cells on the polycaprolactone scaffold. Tissue Engineering & Regenerative Medicine, 2019; 16(4): 395-403.
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Gu Y, Zhang J, Zhang X, Liang G, Xu T, Niu W. Three-dimensional printed Mg-doped β-TCP bone tissue engineering scaffolds: effects of magnesium ion concentration on osteogenesis and angiogenesis in vitro. Tissue Engineering & Regenerative Medicine, 2019; 16(4): 415-429.
5
Goodarzi H, Hashemi-Najafabadi S, Baheiraei N, Bagheri F. Preparation and characterization of nanocomposite scaffolds (collagen/β-TCP/SrO) for bone tissue engineering. Tissue Engineering & Regenerative Medicine, 2019; 16(3): 237-251.
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Hokmabad VR, Davaran S, Aghazadeh M, Alizadeh E, Salehi R, Ramazani A. A comparison of the effects of silica and hydroxyapatite nanoparticles on poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)/chitosan nanofibrous scaffolds for bone tissue engineering. Tissue Engineering & Regenerative Medicine, 2018; 15(6): 735-750.
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Eliaz N, Metoki N. Calcium phosphate bioceramics: a review of their history, structure, properties, coating technologies and biomedical applications. Materials, 2017; 10: 334-339.
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Burton TP, Callanan A. A Non-woven path: electrospun poly(lactic acid) scaffolds for kidney tissue engineering. Tissue Engineering & Regenerative Medicine, 2018; 15(3): 301-310.
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Shafiei-Sarvestani Z, Oryan A, Bigham AS, Meimandi-Parizi A. The effect of hydroxyapatite-hPRP, and coral-hPRP on bone healing in rabbits: radiological, biomechanical, macroscopic and histopathologic evaluation. International Journal of Surgery, 2012; 10(2): 96-101.
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36
ORIGINAL_ARTICLE
Histopathologic Study of the Repair of a Minor Defect in Femur Using Elaeagnus angustifolia Extract in Rabbit
Objective- Veterinary and human orthopedics is widely applied to stimulate fracture healing, accelerate junction connection, and repair bone defects. In this regard, several studies have been conducted on selecting the best material for bone repair. This study aimed to evaluate the effect of aqueous extract of Elaeagnus angustifolia fruit on the process of bone repair in a rabbit animal model.Design- Experimental StudyAnimals- For this purpose, 12 rabbits were obtained.Procedures- Rabbits randomly divided into 3 groups. The control group, in which a two-sided hole was created in the femur and did not receive the treatment. The second group underwent surgery and received an aqueous extract of Elaeagnus angustifolia fruit at a dose of 250 mg/kg, and the third group received 500 mg/kg intraperitoneal. On weeks 2 and 4 following the bone defect, a histopathologic sample was taken from the site. The bone tissue samples were stained with hematoxylin and eosin.Results-According to histopathologic results, the best and weakest performances occurred in the group treated with 500 mg/kg of extract and in the control group, respectively. This group had a significant difference with other groups in terms of osteoplasia (p < 0.05).Conclusion and Clinical Relevance- In general, the results showed that the aqueous extract of Elaeagnus angustifolia can play an important role in the healing of bone fractures.
https://www.ivsajournals.com/article_119966_a569452b8998b599ed740af11bee8a58.pdf
2020-12-01
141
146
10.30500/ivsa.2020.248476.1226
Rabbit
Elaeagnus angustifolia
bone fracture
osteoplasia
Reza
Bajelani
bajelani1@gmail.com
1
Graduate of Veterinary Medicine, Shahrekord Branch Islamic Azad University, Shahrekord, Iran.
AUTHOR
Elham
Moghtadaei-Khorasgani
moghtadaiee@gmail.com
2
Department of Pathobiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
LEAD_AUTHOR
Mehdi
Moghtadaei
3
Department of Orthopedic Surgery, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Loi L, Córdova AJ, Pajarinen TH, Lin ZSB, Goodman SB. Inflammation, fracture and bone repair. Repair, 2016; 86: 119–130.
1
Tu N, Lie D, Wan C. K. Osteoporosis: a review of treatment options. Journal of Pharmacy and Therapeutic, 2018; 3: 92–104.
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Hokmabad VR, Davaran S, Aghazadeh M, Alizadeh E, Salehi R. Effect of incorporating Elaeagnus angustifolia extract in PCL-PEG-PCL nanofibers for bone tissue engineering. Frontiers of Chemical Science and Engineering, 2019; 13: 108-119.
5
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Wang Q, Ruan X, Huang JH, Xu NY, Yan QC. Intra-specific genetic relationship analyses of Elaeagnus angustifolia based on RP-HPLC biochemical markers. Journal of Zhejiang University-Science, 2006; 7: 272-278.
9
Ahmadiani A, Hosseiny J, Semnanian S, Javan M, Saeedi, F. Antinociceptive and anti-inflammatory effects of Elaeagnus angustifolia fruit extract. Journal of Ethnopharmacology, 2000; 72: 287-292.
10
Hosseinzadeh H, Ramezani M, Namjo N. Muscle relaxant activity of Elaeagnus angustifolia L. fruit seeds in mice. Journal of Ethnopharmacology, 2003; 84: 275-278.
11
Rabiei K, Ghobadifar A, Ebrahimzadeh MA, Saeedi M, Mobini M. Effects of ginger and Elaeagnus angustifolia extracts in symptomatic knee osteoarthritis. Journal of Research in Medical Science, 2015; 17: 1-6.
12
Nikniaz Z, Mahdavi R, Ostadrahimi A, Ebrahimi A, Nikniaz L. Effects of Elaeagnus angustifolia L. powder supplementation on serum total antioxidant capacity and malondialdehyde levels in females with knee osteoarthritis. Journal of Herb Medicine, 2015; 5: 177-183.
13
Estai MA, Soelaiman IN,Shuid AN. Histological changes in the fracture callus following the administration of water extract of Piper sarmentosum (Daun Kadok) in estrogen-deficient rats. Iranian Journal of Medical Science, 2011; 36(4): 281–288.
14
ORIGINAL_ARTICLE
Ultrasonographic Evaluation of the Effect of Nigella sativa Oil on Prostate Dimensions in Adult Iranian Mixed-Breed Dogs
Objective- The aim of the present study was to assess the effect of Nigella sativa oil on prostate dimensions in adult dogs.Design- Experimental studyAnimals- Five adult male dogsProcedures- In this research, 5 adult male Iranian mixed-breed dogs with a mean age of 7.30 ± 2.77 years and a mean weight of 27 ± 5.7 kg with clinical symptoms of prostatitis were selected. Sagittal and transverse ultrasound images were performed by using a 5 MHZ convex transducer.Results- In the obtained images desired parameters such as length, width, and height of the prostate gland were measured before and after administration of Nigella sativa. Results showed significant differences between all measured parameters before and after drug administration (p < 0.05).Conclusion and Clinical Relevance- This study confirms that Nigella sativa oil can reduce prostatic dimensions in adult male dogs. So, it can be used as a safe and effective drug for the treatment of prostate-related diseases such as benign prostatic hyperplasia in dogs.
https://www.ivsajournals.com/article_115583_f8ec723a9bb4296d2aa971c9ffd5bd2b.pdf
2020-10-06
147
151
10.30500/ivsa.2020.231895.1216
Ultrasonography
measurements
Nigella sativa
prostate
Iranian mixed-breed dogs
Roham
Vali
rohamvali@gmail.com
1
Department of Clinical Sciences, School of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
LEAD_AUTHOR
Satar
Safarpour
2
D.V.M, School of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
AUTHOR
Yasaman
Daneshvar
3
D.V.M, School of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
AUTHOR
Srinivasan K. Cumin (Cuminum cyminum) and black cumin (Nigella sativa) seeds: traditional uses, chemical constituents, and nutraceutical effects. Food Quality and Safety, 2018; 2(1): 1–16.
1
Ali BH, Blunden, G. Pharmacological and toxicological properties of Nigella sativa. Phytother Research, 2003; 17: 299–305.
2
Debiak, P., Balicki, I. Diagnostic imaging of the canine prostate gland subject to its location and size. Bulletin of the Veterinary Institute in Pulawy, 2009; 53: 313-317.
3
Berry SJ, Coffey DS, Ewing LL. Effects of aging on prostate growth in beagles. American Journal of Physiology, 1986; 250: 1039-1046.
4
Zohil AM, Castellano C. Prepubic and transrectal ultrasonography of the canine prostate: A comparative study. Veterinary Radiology & Ultrasound, 1995; 36: 393-396.
5
Lévy X, Niżański W, von, Heimendahl A, Mimouni P. Diagnosis of common prostatic conditions in dogs: an update. Reproduction in Domestic Animals, 2014; 49: 50-57.
6
Atalan G, Holt PE, Barr FJ, Brown PJ. Ultrasonographic estimation of prostatic size in canine cadavers. Research in Veterinary Science, 1999; 67: 7-15.
7
Padmaa MP. Nigella sativa– A comprehensive review, Indian Journal of Natural Products and Resource, 2010; 1(4): 409-429.
8
Konrad L, Müller HH Lenz C. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Medica, 2000; 66(1): 44-47.
9
Ruel Y, Barthez PY, Mailles A, Begon D. Ultrasonographic evaluation of the prostate in healthy intact dogs. Veterinary Radiology and Ultrasound, 1998; 39(3): 212-216.
10
Atalan G, Barr FJ, Holt PE. Comparison of ultrasonographic and radiographic measurements of canine prostate dimensions. Veterinary Radiology and Ultrasound, 1999; 40: 408-412.
11
Ghadiri A, Avizeh R, Baniadam A, Ranjbar A. comparison of transabdominal and transrectal ultrasonography of the prostate gland in dogs. Iranian Journal of Veterinary Surgery, 2013; 8(2): 43-48.
12
Vali R. Ultrasonographic measurements of prostatic dimensions in adult Iranian mix breed dogs. Journal of Alternative Veterinary Medicine, 2018; 2(5): 266-272.
13
ORIGINAL_ARTICLE
Genomic Detection of Bovine Digital Dermatitis Treponemes in Sole Ulcers
Objective- Evaluation of possible contamination of sole ulcers with digital dermatitis Treponema spp .Design- Clinical detectionAnimals- Thirty-three cows with sole ulcer lesion.Procedures- Hoof trimmings were done by professional veterinarian hoof trimmer on a regular basis. Sole ulcer and digital dermatitis recorded as a wounded lesion in zone 4 and 10 of the hooves during hoof trimming and recorded in special sheets. A total of Thirty-three tissue samples from sole ulcers in zone 4 of digits were taken and the 16S rRNA gene was followed by PCR assay.Results- Annual incidence of clinical digital dermatitis recorded as 7.1 percent as the second prevalent digital lesion in the farm following sole ulcer. Treponema spp . was found in 42 percent of the samples, none of the positive samples show concurrent lesion of digital dermatitis and sole ulcer.Conclusion and Clinical Relevance- Since no concurrent lesions were found in sole ulcer samples, finding Treponema spp. in tissues may be a result of the possible pathogenic presence of the bacteria in this region. Multifactorial causes of sole ulcer make different clinical presentations for the lesion and a microbial cause for the sole ulcer that led to non-healing ulcers were reported.
https://www.ivsajournals.com/article_118154_56581427d71450dd8cf7793fa4cd25fe.pdf
2020-12-01
152
156
10.30500/ivsa.2020.243555.1221
dairy cow
Digital dermatitis
Sole ulcer
PCR
Hoof trimming
Zahra
Ghorbani
1
DVM Graduate, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
AUTHOR
Iraj
Karimi
irkarimi@yahoo.com
2
Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
AUTHOR
Mohamadreza
Mahzounieh
3
Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
AUTHOR
Marzieh
Faezi
4
Damasa Research and Extension Group, Mashhad, Iran.
AUTHOR
Ahmad Reza
Mohamadnia
mohamadnia@um.ac.ir
5
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
LEAD_AUTHOR
Dolecheck K, Bewley J. Animal board invited review: Dairy cow lameness expenditures, losses and total cost. Animal, 2018; 12(7): 1462-1474.
1
Mellado M, Saavedra E, Gaytán L, Veliz FG, Macías-Cruz U, Avendaño-Reyes L, García E. The effect of lameness-causing lesions on milk yield and fertility of primiparous Holstein cows in a hot environment. Livestock Science, 2018; 217: 8-14.
2
Amory JR, Barker ZE, Wright JL, Mason SA, Blowey RW, Green LE. Associations between sole ulcer, white line disease and digital dermatitis and the milk yield of 1824 dairy cows on 30 dairy cow farms in England and Wales from February 2003-November 2004. Preventive Veterinary Medicine, 2008; 83(3-4): 381-391.
3
Charfeddine N, Pérez-Cabal MA. Effect of claw disorders on milk production, fertility, and longevity, and their economic impact in Spanish Holstein cows. Journal of dairy science, 2017; 100(1): 653-665.
4
Whay HR, Waterman AE, Webster AJF, O'Brien JK. The influence of lesion type on the duration of hyperalgesia associated with hindlimb lameness in dairy cattle. The Veterinary Journal, 1998; 156(1): 23-29.
5
Pavlenko A, Bergsten C, Ekesbo I, Kaart T, Aland A, Lidfors L. Influence of digital dermatitis and sole ulcer on dairy cow behaviour and milk production. Animal, 2011; 5(8): 1259-1269.
6
Holzhauer M, Hardenberg C, Bartels CJM. Herd and cow-level prevalence of sole ulcers in The Netherlands and associated-risk factors. Preventive Veterinary Medicine, 2008; 85(1): 125-135.
7
Solano L, Barkema HW, Mason S, Pajor EA, LeBlanc SJ, Orsel K. Prevalence and distribution of foot lesions in dairy cattle in Alberta, Canada. Journal of Dairy Science, 2016; 99(8): 6828-6841.
8
Holzhauer M, Hardenberg C, Bartels CJ, Frankena K. Herd- and cow-level prevalence of digital dermatitis in the Netherlands and associated risk factors. Journal of Dairy Science, 2006; 89(2): 580-588.
9
Yang DA, Heuer C, Laven R, Vink WD, Chesterton RN. Farm and cow-level prevalence of bovine digital dermatitis on dairy farms in Taranaki, New Zealand. New Zealand Veterinary Journal, 2017; 65(5): 252-256.
10
Nowrouzin I. Digital dermatitis; an unrecognised epidemic in dairies in Iran. Proceeding for 1990-91 British Cattle Veterinary Association, 1991: 84-95.
11
Nadi P, Azizzadeh M, Mohamadnia AR. Incidence of hoof lesions in dairy farms in Iran. The First Regional Conference on Cow Comfort and Lameness, 2016; Tehran, Iran.
12
Mohamadnia AR. Occurrence of claw diseases in dairy cattle in Iran. 15th Symposium and 8th Conference on Ruminant Lameness, 2006; Kuopio, Finland.
13
Faezi M, Sangtarash R. Epidemiology of lameness; economic importance, prevalence and incidence. Eltiam, 2020; 6(2): 14-34.
14
Lischer CJ, Ossent P, Räber M, Geyer H. Suspensory structures and supporting tissues of the third phalanx of cows and their relevance to the development of typical sole ulcers (Rusterholz ulcers). Veterinary Record, 2002; 151(23): 694.
15
Shearer JK, van Amstel SR. Pathogenesis and treatment of sole ulcers and white line disease. Veterinary Clinics of North America Food Animal Practice, 2017; 33(2): 283-300.
16
Blowey RW. Digital dermatitis, research and control. Irish Veterinary Journal, 2008; 60: 102-106.
17
Holzhauer M. Non-healing white line lesion, advanced experience. 16th Conference of Lameness in Ruminants, 2011; Rotorua, New Zealand.
18
Evans NJ, Brown JM, Demirkan I, Murray RD, Vink WD, Blowey RW, Hart CA, Carter SD. Three unique groups of spirochetes isolated from digital dermatitis lesions in UK cattle. Veterinary Microbiology, 2008; 130(1-2): 141-150.
19
Yano T, Moe KK, Yamazaki K, Ooka T, Hayashi T, Misawa N. Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis. Veterinary Microbiology, 2010; 143(2-4): 352-362.
20
Evans NJ, Murray RD, Carter SD. Bovine digital dermatitis: Current concepts from laboratory to farm. Veterinary Journal, 2016; 211: 3-13.
21
Evans NJ, Brown JM, Demirkan I, Singh P, Getty B, Timofte D, Vink WD, Murray RD, Blowey RW, Birtles RJ, Hart CA. Association of unique, isolated treponemes with bovine digital dermatitis lesions. Journal of Clinical Microbiology, 2009; 47(3): 689-696.
22
Sykora S, Kofler J, Glonegger-Reichert J, Dietrich J, Auersperg G, Brandt S. Treponema DNA in bovine ‘non-healing’ versus common sole ulcers and white line disease. The Veterinary Journal, 2015; 205(3): 417-420.
23
Evans NJ, Blowey RW, Timofte D, Isherwood DR, Brown JM, Murray R, Paton RJ, Carter SD. Association between bovine digital dermatitis treponemes and a range of 'non-healing' bovine hoof disorders. The Veterinary Record, 2011; 168(8): 214.
24
Klitgaard K, Nielsen MW, Ingerslev HC, Boye M, Jensen TK. Discovery of bovine digital dermatitis-associated Treponema spp. in the dairy herd environment by a targeted deep-sequencing approach. Applied and Environmental Microbiology, 2014; 80(14): 4427-4432.
25
Sullivan LE, Blowey RW, Carter SD, Duncan JS, Grove-White DH, Page P, Iveson T, Angell JW, Evans NJ. Presence of digital dermatitis treponemes on cattle and sheep hoof trimming equipment. Veterinary Record, 2014.
26
Bay V, Griffiths B, Carter S, Evans NJ, Lenzi L, Bicalho RC, Oikonomou G. 16S rRNA amplicon sequencing reveals a polymicrobial nature of complicated claw horn disruption lesions and interdigital phlegmon in dairy cattle. Scientific Reports, 2018; 8(1): 1-2.
27
Kofler J. Pathogenesis and treatment of toe lesions in cattle including "nonhealing" toe lesions. Veterinary Clinics of North America Food Animal Practice, 2017; 33(2): 301-328.
28
ORIGINAL_ARTICLE
Telangiectatic Osteosarcoma in a Budgerigar (Melopsittacus undulatus) - Pathological Findings
Background- Neoplastic diseases are one of the main factors that threaten the life span of pet birds. Osteoma and osteosarcoma are considered as the most prevalent of neoplasms in the skeletal system, which were reported in several species of the birds.Case Description- This paper describes gross and histopathological features of telangiectatic osteosarcoma in an adult male budgerigar (Melopsittacus undulatus) with weakness, general depression and weight loss. Clinical Findings- At necropsy, a firm mass with approximately one cm in size and brown color involved the tibiotarsus. Pathology examination of the mass indicated bloody cystic lesions accompanied by occasional spicules of osteoid between pleomorphic mesenchymal cells, which it was found minimal. Clinical Relevance- Telangiectatic osteosarcoma should be differentiated from either hemangiosarcoma or aneurysmal bone cyst. This is the first report of osteosarcoma in the budgerigar.
https://www.ivsajournals.com/article_107070_e0f48c700dda856ce7660f10a53fb6be.pdf
2020-12-01
157
159
10.30500/ivsa.2020.211743.1205
osteosarcoma
tibiotarsus
Budgerigar
Pathology
Monireh
Khordadmehr
khordadmehr@tabrizu.ac.ir
1
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
LEAD_AUTHOR
Javad
Ashrafi-Helan
ashrafihelan@yahoo.com
2
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
AUTHOR
Dara
Azizi
dara.azizi.96@gmail.com
3
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
AUTHOR
Sadegh
Haghparast
s.haghparast.k@gmail.com
4
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
AUTHOR
Schmidt RE, Reavill DR, Phalen DN. Pathology of pet and aviary birds. 2nd ed. JohnWiley & Sons, Inc., 2015; 199-220
1
Klein MJ and Siegal GP. Osteosarcoma. Anatomic and histologic variants. American Journal of Clinical Pathology, 2006; 125: 555-581.
2
Thampson KG, Dittmer KE. Tumors of bone. In: Meuten DJ, edr. Tumors in Domestic Animals. 5th ed. John Wiley & Sons, Inc., 2017; 357-424.
3
Mueller f, Fuchs B, Kaser-Hotz B. Comparative biology of human and canine osteosarcoma. Anticancer Research, 2007; 27: 155-164.
4
Simova-Curd S, Nitzl D, Mayer J and Hatt JM. Clinical approach to renal neoplasia in budgerigars (Melopsittacus undulatus). Journal of Small Animal Practice, 2006; 47: 504–511.
5
Nair V. Neoplastic diseases In: Swayne DE, edr. Diseases of Poultry. 13th ed. John Wiley & Sons, Inc., 2013; 604-675.
6
Payne LN and Nair V. The long view: 40 years of avian leukosis research. Avian Pathology, 2012; 41: 1-9.
7
Reece RL. Observations on naturally occurring neoplasms in birds in the state of Victoria, Australia, Avian Pathology, 1992; 21(1): 3-32.
8
ORIGINAL_ARTICLE
Ocular Dermoid Cyst in a Four-Month-Old Holstein Calf
Case Description- A four-month-old female Holstein calf was presented to the Veterinary Teaching Hospital of Urmia University with a history of abnormal hairy growth on the right eye since birth.Clinical Findings- On general examination, the animal was alert. Body temperature, heart rate, respiratory rate, menace test, and pupillary light reflex were normal. On ophthalmic examination, a hairy mass was observed on the conjunctivae, third eyelid, sclera, and cornea of the right eye. Histopathological examination revealed the mass with three distinct areas of skin. It was diagnosed as an ocular dermoid cyst and surgical treatment was warranted.Treatment and Outcome- The mass was surgically excised to prevent damage to the anterior chamber of the eye. Ocular healing was satisfactory in a 4 week follow up.Clinical Relevance- This report described an ocular dermoid cyst in a four-month Holstein calf. There was just lacrimation, possibly due to irritation caused by the hairs. The ocular dermoid cyst could be excised surgically, and the prognosis is good.
https://www.ivsajournals.com/article_105780_b190dad92c3cea60c8f911399007eba3.pdf
2020-12-01
160
163
10.30500/ivsa.2020.211093.1204
Dermoid cyst
Holstein calves
Eye
histopathology
Rahman
Allahvirdizadeh
vahnm56@gmail.com
1
Department of Internal Medicine, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
AUTHOR
Rahim
Mohammadi
r.mohammadi@urmia.ac.ir
2
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
AUTHOR
Aliasghar
Tehrani
manijehid@yahoo.com
3
Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
AUTHOR
Vahid
Najarnezhad
v.najarnezhad@urmia.ac.ir
4
Department of Internal Medicine, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
LEAD_AUTHOR
Nishie A, Yoshimitsu K, Honda H, Irie H, Aibe H, Shinozaki K, Mizumoto K, Matsuo Y, Masuda K. Presacral dermoid cyst with scanty fat component: usefulness of chemical shift and diffusion-weighted MR imaging. Computerized Medical Imaging and Graphics, 2003; 27: 293–296.
1
Moore CP, Shaner JB, Halenda RM, Rosenfeld CS, Suedmeyer WK. Congenital ocular anomalies and ventricular septal defect in a dromedary camel (Camelus dromedarius). Journal of Zoo and Wildlife Medicine, 1999; 30(3): 423-430.
2
Yeruham I, Perl S, Liberboim M. Ocular dermoid in dairy cattle - 12 years survey. Revue de Médecine Vétérinaire, 2002; 153(2): 91-92.
3
Barkyoumb SD, Leipold HW. Nature and cause of bilateral ocular dermoids in Hereford cattle. Veterinary Pathology, 1984; 21(3): 316-324.
4
Lawson DD. Corneal dermoids in animals. Veterinary Record, 1975; 97: 449-450.
5
Constable PD, Hinchcliff KW, Done SH, Grunberg W. Veterinary Medicine: A textbook of the diseases of cattle, sheep, goats, pigs and horses. 11th ed. Saunders Elsevier. Philadelphia, 2017.
6
Golubovic SZ, Latkovic Z, Horvatic-Obradovic M. Surgical treatment of large corneal dermoid. Documenta Ophthalmologica, 1995; 91(1): 25-32.
7
Kiliç N. Cardiopulmonary, biochemical, and haematological changes after detomidine-midazolam-ketamine anaesthesia in calves. Bulletin of the Veterinary Institute in Pulawy, 2008; 52(3): 423-426.
8
Hillyer LI, Jackson AP, Quinn GC, Day MJ. Epidermal (infundibular) and dermoid cysts in the dorsal midline of a three-year-old thoroughbred-cross gelding. Veterinary Dermatology, 2003; 14(4): 205–209.
9
Sarrafzadeh-Rezaei F, Farshid AA, Saifzadeh S. Congenital ocular dermoid cyst in a river buffalo (Bubalus bubalis) calf. Journal of Veterinary Medicine Series A, 2006; 54: 51-54.
10
Kılıç N, Toplu N, Epikmen ET. Surgical Treatment of Corneal Large Dermoid in a Simmental Calf. Acta Scientiae Veterinariae, 2012; 40(2): 1-5.
11
Mansour AM, Barber JC, Reinecke RD. Wang FM. Ocular choristomas. Survey of Ophthalmology, 1989; 33(5): 339-358.
12
Tunio A, Bughio S, Abro SH, Kalhoro DH, Memon AA. Eye dermoid in a thari breed cattle calf and its surgical management: A case study. Pakistan Journal of Agriculture Engineering and Veterinary Sciences, 2016; 32(2): 295-299.
13
Bekele T, Bhokre AP, Mekonnen B, Tesfaye W, Alemu B, Tintagu T, Gebrekidan B. Ocular dermoid in crossbred calf- A case report. Ethiopian Veterinary Journal, 2014; 18(1): 105-108.
14
ORIGINAL_ARTICLE
Surgical Management of the Trauma-Induced Abomaso-Cutaneous Fistula in a Lamb
Case Description- The most important causes of abomasal fistulation have been described in association with umbilical hernia and infection and trauma. A 2-month-old male lamb with an open orifice on the ventral abdomen was referred to the veterinary teaching hospital (VTH) of Lorestan University.Clinical Findings- In this case, the lamb had the abomaso-cutaneous fistula due to unknown penetrating trauma. According to the owner's claim, the above-mentioned non-painful orifice was occurred in the ventral midline due to the rupture of abdominal swelling approximately 45 days ago. On physical examination, heart rate, respiratory rate, and body temperature were normal, but CBC showed slight neutrophilia and mild anemia.Treatment and Outcomes- After local anesthesia around the fistula, the abomasum adhering to the ventral muscular ring was dissected and closed. Then the muscular ring was closed in a vertical mattress pattern and subcutaneous tissue and skin were sutured in the usual method.Clinical Relevance- During the fistula examination through the surgical operation, a muscular ring surrounded by fibrous margins was observed with partial abomasal herniation from the muscular defect. Seemed that adhesion between the abomasum and subcutaneous tissue had prevented the development of diffused peritonitis. Early proper surgical intervention is useful for the treatment of trauma-induced abomaso-cutaneous fistulae in ruminants.
https://www.ivsajournals.com/article_95799_b3d3bd60d66441c0b598e0c8690a42ee.pdf
2020-12-01
164
167
10.30500/ivsa.2019.152488.1162
lamb
abomaso-cutaneous fistula
Surgery
Abbas
Raisi
raisi.a@lu.ac.ir
1
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
LEAD_AUTHOR
Ali
Aleseyedan
alias110156@gmail.com
2
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Afshar
Roomiani
afsharroomiani@yahoo.com
3
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Amir
Zakian
amir.zakian7@gmail.com
4
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Peyman
Esmaeili Fard Barzegar
vet.20pe@yahoo.com
5
Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.
AUTHOR
Fubini SL, Smith DF. Umbilical hernia with abomasal-umbilical fistula in a calf, Journal of the American Veterinary Medical Association, 1984; 184: 1510.
1
Newcomb R, Morton TC. A Case of abomaso-umbilical fistula in a calf. Veterinary Record, 1970; 87(26): 803.
2
Parker JE, Fubini SL. Abomasal fistulas in dairy cows, The Cornell Veterinarian, 1987; 77(4): 303-309.
3
Tulleners EP, Donawick WJ. Secondary closure of infected abdominal incisions in cattle and horses. Journal of the American Veterinary Medical Association, 1983; 182(12): 1377-1379.
4
Sobti VK, Saini NS, Singh KI, Bansal PS, Simran PS. Surgical management of abomasal herniation and its fistulation in a buffalo. Indian Veterinary Journal, 1998; 75(11): 1046-1047.
5
Al-Sobayil FA, Ahmed AF. Surgical treatment for different forms of hernias in sheep and goats, Journal of Veterinary Science, 2007; 8(2): 185-191.
6
Baxter GM. Umbilical enterocutaneous fistula. Compend Equine, 2007; 2: 96-99.
7
Bristol DG. Enterocutaneous fistulae in horses: 18 cases (1964 to 1992). Veterinary Surgery, 1994; 23(3): 167-171.
8
Vandana S, Ashwani K, Kiranjeet S, Mahajan SK. Umbilical hernia with abomasal–umbilical fistula in a cow calf, Vet. Scan, 2011; 6(1): 83.
9
Sutradhar BC, Hossain MF, Das BC, Kim G, Hossain MA. Comparison between open and closed methods of herniorrhaphy in calves affected with umbilical hernia. Journal of Veterinary Science, 2009; 10(4): 343-347.
10
Azizi S, Kazemi-Darabadi S, Bartafteh E. Surgical management of the trauma-induced colocutaneous fistula in a horse. Journal of Equine Veterinary Science, 2013; 33: 901-904.
11
Vertenten G, Declercq J, Gasthuys F, Devisscher L, Torfs S, van Loon G, Martens A. Abomasal end-to-end anastomosis as treatment for abomasal fistulation and herniation in a cow. The Veterinary Record, 2009; 164(25): 785.
12
Bailey JV, Fretz PB. Attempts at surgical correction of unusual colonic fistulae in the horse. The Canadian Veterinary Journal, 1983; 24(7): 222-223.
13
ORIGINAL_ARTICLE
Treatment of Hoof Disease in an Asian Elephant (Elephas maximus) Using Creative Surgery: A Successful Case Report
Case Description- Chronic foot disease, which is considered a tremendous clinical challenge, poses a serious threat to the overall health of elephants. We treated an Asian elephant with hoof disease by a creative surgery.Clinical Findings- An Asian elephant presented with hoof disease, which caused the partial detachment of its right hind foot-pad.Treatment and Outcome- We fixed the elephant’s foot by using an artificial steel plate and sternal wire, At the same time we adjusted diet. Elephant hoof disease is cured and its function restored.Clinical Relevance- The utilization of fixation plates can be extremely useful for the treatment of hoof disease in the elephant.
https://www.ivsajournals.com/article_108127_67374e5280842384e7fcbca029a90ac4.pdf
2020-12-01
168
172
10.30500/ivsa.2020.224068.1211
elephant
hoof disease
treatment
Guanghao
Lin
dr_weipeng@163.com
1
Plastic Repair Reconstructive Surgery Department, Ningbo First Hospital, Ningbo, China.
AUTHOR
Liming
Chen
1770017918@qq.com
2
Animal Management Department, Ningbo Youngor Zoo, Ningbo, China.
AUTHOR
Youfeng
Xu
3
Department of Ultrasound, Ningbo First Hospital, Ningbo, China.
AUTHOR
Peng
Wei
dr_weipeng@163.com
4
Plastic Repair Reconstructive Surgery Department, Ningbo First Hospital, Ningbo, China.
LEAD_AUTHOR
Clubb R, Rowcliffe M, Lee P, Mar KU, Moss C, Mason GJ. Compromised survivorship in zoo elephants. Science, 2008; 322(5908): 1649.
1
Galateanu G, Hildebrandt TB, Maillot A, Etienne P, Potier R, Mulot B, Saragusty J, Hermes R. One small step for rhinos, one giant leap for wildlife management--imaging diagnosis of bone pathology in distal limb. PLoS One, 2013; 8(7): e68493.
2
Haspeslagh M, Stevens JM, De Groot E, Dewulf J, Kalmar ID, Moons CP. A survey of foot problems, stereotypic behaviour and floor type in Asian elephants (Elephas maximus) in European zoos. Animal Welfare, 2013; 22(4): 437-443.
3
Lahiri-Choudhury DK. Historical Lessons for the Treatment of Foot Diseases in Captive Asian Elephants. Lowa State University, 2008; 79-83.
4
Mehren KG. The Elephant's Foot: Prevention and Care of Foot Conditions in Captive Asian and African Elephants. Australian Veterinary Journal, 2010; 79(12): 824-824.
5
Sadler WC. The Role of Nutrition and its Possible Impact on Elephant Foot Care. Iowa State University, 2008; 13-15.
6
ORIGINAL_ARTICLE
Retraction: Topical Application of Natural Urmia Honey on Experimental Burn Wounds in the Dog: Clinical and Microbiological Studies
The editors of the journal are retracting this article published previously in the Iranian Journal of Veterinary Surgery.1 The aforementioned article was published in 2007 when the journal did not have an online submission system, yet. Recently, we realized that this article had been published elsewhere at the same time.2 We could not determine which article was published first because of a lack of submission history in our system as mentioned above and changes in the editorial staff of the journal over time. More importantly, the corresponding author of the article was regretfully passed away in a plane crash in 2011, therefore, we could not investigate which journal had received the manuscript first. As a result, we decided to retract the article because of redundant publication.
https://www.ivsajournals.com/article_114759_6a748b415f73c0b82ad8d02944b61d90.pdf
2020-12-01
173
173
Shokouhi Sabet Jalali F, Tajik H, Saifzadeh S, Fartash B. Topical Application of Natural Urmia Honey on Experimental Burn Wounds in the Dog: Clinical and Microbiological Studies. Iranian Journal of Veterinary Surgery, 2007; 2(2): 13-21.
1
Shokouhi Sabet Jalali F, Tajik H, Saifzadeh S, Fartash B. Topical Application of Natural Urmia Honey on Experimental Burn Wounds in the Dog: Clinical and Microbiological Studies. Asian Journal of Animal and Veterinary Advances, 2007; 2(3): 133-139.
2