@article { author = {Molaei, Mohammad Mahdi and Azari, Omid and Sakhaee, Ehsanollah and Naderi, Zahedeh and Mehdizadeh, Sara}, title = {Comparison of Lidocaine, Xylazine, and a Combination of Lidocaine and Xylazine for Caudal Epidural Analgesia in Dromedary Camels}, journal = {Iranian Journal of Veterinary Surgery}, volume = {05}, number = {1-2}, pages = {51-62}, year = {2010}, publisher = {Iranian Veterinary Surgery Association (IVSA)}, issn = {2008-3033}, eissn = {2676-6299}, doi = {}, abstract = {Objective- This study was performed to investigate the analgesic effects of lidocaine, xylazine and lidocaine/xylazine combination in epidural anesthesia in dromedary camels.Design- Experimental StudyAnimals- Fifteen healthy immature dromedary camelsMethods- The camels were randomly designed in 3 equal groups. In group L: lidocaine 2% (0.22 mg/kg), in group X: xylazine 2% (0.17 mg/kg), and in group LX: a combination of lidocaine 2% (0.22 mg/kg) and xylazine 2% (0.17 mg/kg) were injected into the first intercoccygeal epidural space. Analgesia, sedation, ataxia, and effect on cardiopulmonary, rectal temperature were recorded at different intervals before (baseline) and after the drug administration.Results- Epidural lidocaine, xylazine and their combination produced analgesia in the tail, anus and perineum. Onset time of perineal analgesia in groups L and LX was significantly shorter than group X. Duration of complete perineal analgesia in group X and LX was significantly longer than group L. Mild to moderate sedation was observed in groups X and LX, whilst the camels in group L were alert and nervous during the study. Ataxia was observed in all test subjects and was more severe in group L and LX. Significant depression in heart rate, respiratory rate, and rectal temperature values were observed in groups X and LX in some measurement points of the study.Conclusion and Clinical Relevance- According to the results of present study, it could be concluded that a combination of lidocaine and xylazine administered epidurally to dromedaries produces an effective, safe, with more rapid onset of longer perineal analgesia, when compared with either agent alone.}, keywords = {Epidural,Lidocaine,Xylazine,Dromedary Camels}, url = {https://www.ivsajournals.com/article_3143.html}, eprint = {https://www.ivsajournals.com/article_3143_a94fdae2ff9a52d0bc4416ce2d723e61.pdf} }